A great deal of work-related stress is caused by working practices that are out of date, according to one expert.
Citing figures produced by the Health and Safety Executive (HSE), Work Wise UK states that 12.8 million working days were lost through stress and depression in 2004-05.
Additionally, more than a third of all new instances of ill health are associated with work-related stress, according to the HSE.
Blaming "outmoded" practices for this level of work-related stress, Phil Flaxton, chief executive of the organisation, said that working from a central location which involves long commutes and "inflexible" hours has a negative effect upon workers.
"The social impact of work is considerable. The health cost, as well as the impact on family life, must be huge," he remarked.
Launching National Work from Home Day earlier in the month, Mr Flaxton said that allowing staff to work from home helps to improve levels of productivity and creates a better work-life balance for employees.